Dr. Hany Sobhi

faculty

Hany Sobhi PhD

Professor of Chemistry
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Science and Technology Center
2nd Floor, Room 229

2500 W North Ave
Baltimore, MD 21216

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Organic & Clinical Chemistry (Biomarkers & Lipid Research)
Forensic Chemistry (Toxins & Drug Analysis)
Polymer Chemistry (Biomedical Applications)
Biography

Dr. Sobhi obtained his Ph.D. in Clinical Bioanalytical Chemistry, with a specialization in synthetic bioorganic chemistry from Cleveland State University in 2008. Following his M.S. in Synthetic Organic Chemistry in 2005. In 2008 he was appointed as an NIH Post-Doctoral Fellow, at the Center for Mitochondrial Diseases at the Department of Pharmacology, at Case Western Reserve University, School of Medicine. In 2019 Dr. Sobhi was promoted to the rank of full Professor of organic and clinical chemistry at Coppin State University. Since 2011, Dr. Sobhi has established his research lab (Center for Organic Synthesis). Shortly after he was awarded the Minority-Serving Institution Faculty Scholar in Cancer Research Awards from the American Association for Cancer Research (AACR). In 2012 Dr. Sobhi received NASA / NAI Astrobiology Faculty Fellowship, and in 2013 he was awarded the NAP-NASA/ MIRS- Award 2013 and was appointed as visitor scientist at NASA. In 2015 Dr. Sobhi was awarded the Wilson H. Elkins Professorships, from the University System of Maryland.  Furthermore, Dr. Sobhi is the recipient of the 2015/2016 University System of Maryland Board of Regents Faculty award USM/ BOR Board for excellence in research and innovation. Most Recently in May 2023 Dr. Sobhi was awarded the Egale Excellence in Research Faculty award for 2023.

For the past twelve years the center for organic Synthesis has received several grants from National Institute of Health (NIH), Department of Defense (DOD), NASA and USDA, to support the ongoing research efforts.  Dr. Sobhi research team is all undergraduate and graduate chemistry and biology students, and he engages his students in the research projects and, secure funds for student’s research scholarships. The primary objective of Dr. Sobhi’s research is to develop strategies to synthesis small bioorganic molecules that can be used for clinical diagnosis (biomarkers) and understand the pathogenic mechanisms underlying the clinical manifestations of diseases which could be clinically useful in treatment. Dr. Sobhi has published numerous papers in peer-reviewed journals and has presented his research at national and international conferences. Dr. Sobhi is an active member of several professional scientific research organizations. Currently his most recent publication received an honorary award by the American Physiological Society for APSelect (http://apsselect.physiology.org/ ) and has been selected as one of the best recently published articles in Physiological Research. Dr. Sobhi had extended Coppin State University outreach and research network to several national and international research institution, and he established network of collaborators with federal agencies, such as NASA-GSFC, department of defense DOD APG-Army Research laboratory and Department of Homeland security- DHS- CSAC- chemical Security Analysis Center. 

  • Novel odd-chain cyclopropane fatty acids:  detection in the mammalian lipidome and uptake by hepatosplanchnic tissues, Hany F. Sobhi1†, Kelly E. Mercer2,3,*, Renny S. Lan2,3, Laxmi Yeruva2,4, Sean H. Adams6,7† et al,  submitted for publication, with the Journal of Lipid Research, Manuscript Number: JLR-D-24-00043R1 January 22, 2024, Accepted on August 22, 2024
  • Effect of Quorum Sensing Molecules on the Quality of Bacterial Nanocellulose Materials, Rabih E. Jabbour1, Joshua S. Kang*2, Hany F. Sobhi*2 Manuscript submitted for publication, with the Journal: ACS Omega Manuscript ID: ao-2023-10053d submitted December 15, 2023, Accepted on April 08. 2024, ACS Omega. 2024 May 7; 9(18): 20003–20011.doi: 10.1021/acsomega.3c10053 PMCID: PMC11079910 PMID: 38737048, Published  on May 07, 2024
  • Investigation of thermal and rheological properties of surface modified polydimethylsiloxane (PDMS) for medical device application, Hany F. Sobhi1*, Tochi Iwuji1 and Keturah Postell1 PAPER ID: 3997725 Division of Polymer Chemistry. 265th American Chemical Society | New Orleans, LA | March 19, 2024
  • Qualitative Analysis & Characterization of Cyclopropyl Fatty acids from Plasma Hany F Sobhi, Kaylah Castillo, Ashley Roman & Sean Adams, PAPER ID: 3820070 DIVISION: Division of Biological Chemistry. 263rd American Chemical Society | Indianapolis, IN |March 26-30, 2023.
  • T3P-Promoted Synthesis of a Series of 2-Aryl-3-phenyl-2,3-dihydro-4H-pyrido[3,2-e] [1,3]thiazin-4-ones and Their Activity against the Kinetoplastid Parasite Trypanosoma brucei. Lee J. Silverberg 1,* , Tapas K. Mal 2, Carlos N. Pacheco and Hany F. Sobhi 7 et al-Published: 9 October 2021, Molecules 2021, 26(20), 6099; https://doi.org/10.3390/molecules26206099 | October 09, 2021
  • Qualitative Analysis & Characterization of Cyclopropyl Fatty acids from Plasma Hany F Sobhi, Kaylah Castillo, Ashley Roman & Sean Adams, PAPER ID: 3820070 DIVISION: Division of Biological Chemistry. 263rd American Chemical Society | Indianapolis, IN | March 26-30, 2023
  • T3P-Promoted Synthesis of a Series of 2-Aryl-3-phenyl-2,3-dihydro-4H- pyrido[3,2-e] [1,3]thiazin-4-ones and Their Activity against the Kinetoplastid Parasite Trypanosoma brucei. Lee J. Silverberg 1,* , Tapas K. Mal 2, Carlos N. Pacheco and Hany F. Sobhi 7 et al . / Published: 9 October 2021, Molecules 2021, 26(20), 6099; https://doi.org/10.3390/molecules26206099 | October 09, 2021
  • Synthesis and Characterization of substrates for grafting polymers used in medical plastic, Meghan R. Johnston1* Hany F. Sobhi2 Alaa El Hajjar1, manuscript ID : CDC- D-2-00085 submitted to the Journal, Chemical Data Collections, on March 4, 2020, revised on November 15, 2020, Accepted on December 08, 2020, Published on Chemical Data Collection 31 ( 2021 ) 100621, https://doi.org/10.1016/j.cdc.2020.100621 | February 01, 2021.
  • Antifungal activity of 2,3-diphenyl-2,3-dihydro-1,3-thiaza-4-ones against two human pathogenic fungi" Livia Liporagi Lopes, Hany F. Sobhi, Lee Silberberg, Radames Cordero, and Arturo Casadevall. The manuscript submitted to the American Society of Microbiology Journal, Antimicrobial Agents and Chemotherapy. Manuscript control number AAC01358-20, bioRxiv preprint DOI: https://doi.org/10.1101/2020.06.27.175711 Posted: June 27, 2020, Version 1
    | June 27, 2020
  • Carnitine palmitoyltransferase 2 (CPT2) knockout potentiates palmitate‐induced insulin resistance in C2C12 myotubes, Michael L. Blackburn1,2, Kikumi Ono- Moore1, Hany F. Sobhi3, and Sean H. Adams1,2† American Journal of Physiology‐Endocrinology and Metabolism. PMID: 32459525 DOI:10.1152/ajpendo.00515.2019. 2020 Aug 1; Volume 319, Issue # (2): E265‐E275. https://doi.org/10.1152/ajpendo.00515.201doi: 10.1152/ajpendo.00515.201, Epub 2020 May 27. PMID: 32459525 | August 01, 2020
  • Director Center for Organic Synthesis
  • Co-Director NIH- IRACDA Program
  • Post-Doctorate Fellow, Synthetic Organic Chemistry, Case Western Reserve University 2010
  • Ph.D. Clinical Bio-Analytical Chemistry, Cleveland State University, 2008
  • M.Sc. Organic Chemistry, Cleveland State University, 2008
  • B.Sc. Chemistry, Alexanderia University, 1993

Dr. Sobhi is an active member of several professional scientific research organizations. Currently his most recent publication received an honorary award by the American Physiological Society for APSelect (http://apsselect.physiology.org/) and has been selected as one of the best recently published articles in Physiological Research.

  • American Chemical Society (Organic / Polymer Divisions) ‐ACS
  • American Physiological Society APS
  • American Society for Microbiology‐ASM
  • The American Society for Biochemistry and Molecular Biology ‐ASBMB
  • American association For Cancer Research ‐ AACR
  • American Society for Applied Spectroscopy ‐ASAS
  • Association of the United States Army- AUSA
  • North Coast Thermal Analysis Society – NCTA

Dr. Sobhi’s research is to develop strategies to synthesis small bioorganic molecules that can be used for clinical diagnosis (biomarkers) and understand the pathogenic mechanisms underlying the clinical manifestations of diseases which could be clinically useful in treatment. Dr. Sobhi has published numerous papers in peer-reviewed journals and has presented his research at national and international conferences. Dr. Sobhi is an active member of several professional scientific research organizations. Currently his most recent publication received an honorary award by the American Physiological Society for APSelect (http://apsselect.physiology.org/ ) and has been selected as one of the best recently published articles in Physiological Research.

  • 2023    Eagle Award of Excellence In Research Award, Division of Academic Affair, CSU, May 04, 2023
  • 2020    American Physiological Society Award, for the APS Select Publication With the American Journal of Physiology Endocrinology and Metabolism Vol. 318, No. 5, 2020
  • 2016    University System of Maryland, USM Board of Regents Faculty Award, USM – BOR, for research, and innovation
  • 2015    Wilson H. Elkins Faculty Award, from the University system of Maryland USM Board of Regents Faculty (USM) Award, USM – BOR, for research, and innovation
  • 2013    NASA - NAI- MIRS Astrobiology Faculty Incentive Research Award
  • 2012    NASA -NAI-Astrobiology Faculty Fellowship Program Faculty Scholar Research Award. June 4, 2012
  • 2011    American Association for Cancer Research, AACR Faculty Scholar in Cancer Research Award
  • 2011    Distinguished Faculty research and development Award, from Coppin State University n Research Council.
  • 2009    Postdoctoral Research Award, Research Showcase Case Western Reserve University. April16-2009
  • 2007    F.C. Mark Graduate Teaching Assistantship Award for Excellence in Teaching Organic Chemistry
  • 2007    Doctoral Dissertation Research Expense Award, Cleveland State University, University Research Council
  • 2006    F.C. Mark Graduate Teaching Assistantship Award for excellence in teaching NMR and Organic Chemistry Laboratories

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